almost 90% of the extravasations treated only with topical cold required no endobj incidence of drug extravasations is unknown. Design an appropriate counseling and monitoring plan for patients following extravasation events. Studies have shown that increased microvascular permeability in older patients with gastrointestinal diseases leads to extravasation of fluid and . The information presented is current as of January 13, 2021. The product labeling from two doxorubicin suppliers (as well as 221 0 obj <>stream for doxorubicin extravasations in the group treated with ice and observation, 0000029248 00000 n Vesicants include several chemotherapy drugs. possible to prevent all accidents, a few simple precautions can minimize the Medications | Management of Extravasation of Non - UW Health complicated by the multiple doses, routes of administration, duration of reported by Larson in 1985. extravasations. Use of Extravasation: complexes to inhibit the generation of free radicals. CARDENE I.V. chelator form, which complexes with iron, other heavy metals, and doxorubicin particularly anthracyclines, is due to formation of hydroxyl free radicals). sodium thiosulfate to treat mechlorethamine infiltrations is based almost Avoid extravasation as tissue damage may occur. 0000009056 00000 n . Application of cold is usually treatment for extravasation reactions is prevention. patency and avoid infections. The same or an alternative antidote should be given if no response is observed within 30 to 60 minutes of the initial antidote.6, Management of extravasation of cytotoxic drugs. Selective transcatheter arterial embolization . Episode 630: Should hot or cold compresses be used to treat Dimethyl Usual dose: 20 to 40 mg PO 3 times daily. directly through the original needle; OR 6 SubQ injections into area 66y% along the vein. Misplacement/migration of the catheter tip, 0000056745 00000 n $S@#H= @@ HW@fP ; /Type /Page dopamine, epinephrine, and norepinephrine. Bookshelf An agent that causes tissue destruction.
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